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产品信息
PA5-41438
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human PITX1 (aa 265-314).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2608280
产品详细信息
Peptide sequence: GTPASPYSVY RDTCNSSLAS LRLKSKQHSS FGYGGLQGPA SGLNACQYNS
Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 93%; Mouse: 93%; Rat: 93%; Zebrafish: 79%
靶标信息
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hindlimb expressed homeobox protein backfoot; Hindlimb-expressed homeobox protein backfoot; Homeobox protein P-OTX; Homeobox protein PITX1; OTX; paired-like homeodomain 1; Paired-like homeodomain transcription factor 1; pituitary homeo box 1; Pituitary homeobox 1; Pituitary OTX-related factor
基因别名: BFT; CCF; LBNBG; P-OTX; PITX1; POTX; PTX1
UniProt ID: (Human) P78337, (Mouse) P70314
Entrez Gene ID: (Human) 5307, (Mouse) 18740
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription factor binding
protein binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
homeodomain transcription factor
skeletal system development
transcription from RNA polymerase II promoter
anatomical structure morphogenesis
branchiomeric skeletal muscle development
pituitary gland development
embryonic hindlimb morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
myoblast fate commitment
cartilage development
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
hindlimb morphogenesis
