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PKM2 Antibody (A303-660A) in IHC
Detection of human PKM2 by immunohistochemistry. Samples: FFPE sections of human osteosarcoma. Antibody: Affinity purified rabbit anti- PKM2 Cat. No. A303-659A Lot1 used at a dilution of 1:1,000 (1µg/ml) (left) and Cat. No. A303-660A Lot1 used at a dilution of 1:5,000 (0.2µg/ml) (right). Detection: DAB.
产品信息
A303-660A
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 481 and 531
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, Chicken, Rabbit, Cat and Orangutan
靶标信息
PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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