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Keep as concentrated solution.
Predicted reactivity: Mouse (98%), Rat (99%), Rhesus Monkey (100%), Bovine (98%).
Positive Control: Target recombinant protein.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Inactive phospholipase C-like protein 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; Phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; Phospholipase C-related but catalytically inactive protein; PLC-L1; PRIP; protein phosphatase 1, regulatory subunit 127
基因别名: C230017K02Rik; PLC-L; PLC-L1; PLCE; PLCL; PLCL1; PLDL1; PPP1R127; PRIP; PRIP-1
UniProt ID: (Human) Q15111, (Mouse) Q3USB7
Entrez Gene ID: (Human) 5334, (Mouse) 227120