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Sequence of this protein is as follows: MHSQVFSAFP YSLPLRFWVN VIKNPQFVFD IHKGSITDAC LSVVAQTFMD SCSTSEHRLD KDSPSNKLLY AKDIPSYKSW VERYYADIAK LPAISDQDMN AYLAEQSRLH AVEFNMLSAL NEIYSYVSKY SEELIGALEQ DEQARRQRLA YKVEQLINAM SIES
Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Drosophila plexin-A is a receptor for class I semaphorins and controls motor and axon guidance. Plexin-A3 mediates cell-repelling cues. Plexins B and C are receptors for Sema 4 and Sema 7, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ11751; FLJ30634; Plex 2; plexin 2; plexin-2; Plexin-A2; Semaphorin receptor OCT; transmembrane protein OCT
基因别名: 2810428A13Rik; AA589422; AW457381; KIAA0463; mKIAA0463; OCT; PlexA2; PLXN2; PLXNA2; UNQ209/PRO235
UniProt ID: (Human) O75051, (Mouse) P70207
Entrez Gene ID: (Human) 5362, (Rat) 289392, (Mouse) 18845