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Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: differentially expressed in brain tumors; MM1; MM1KIAA0315dJ402G11.3; Plexin-B2
基因别名: Debt; dJ402G11.3; KIAA0315; MM1; Nbla00445; PLEXB2; plexin-B2; PLXNB2
UniProt ID: (Human) O15031, (Mouse) B2RXS4
Entrez Gene ID: (Human) 23654, (Mouse) 140570