Invitrogen

PLXNB2 Polyclonal Antibody

PLXNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PLXNB2 Antibody (PA5-47721) in IHC (P)

Immunohistochemical analysis of PLXNB2 in immersion fixed paraffin-embedded sections of human colon cancer. Samples were incubated in PLXNB2 polyclonal antibody (Product # PA5-47721) using a dilution of 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-basic. Tissue was stained with the Anti-Sheep HRP... View More

PLXNB2 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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产品信息

PA5-47721

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

免疫组化（石蜡） (IHC (P))

5-15 µg/mL

免疫组化（冰冻） (IHC (F))

5-15 µg/mL

产品规格

种属反应

Human

宿主/亚型

Sheep / IgG

分类

Polyclonal

类型

Antibody

抗原

CHO-derived recombinant human Plexin B2 Leu20-Arg1160

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2610394

产品详细信息

In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) Plexin A1, rmPlexin A2, recombinant human (rh) Plexin A4, rhPlexin B1, rhPlexin B3, rhPlexin C1 and rhPlexin D1 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.

仅用于科研。不用于诊断过程。未经明确授权不得转售。