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产品信息
PA5-72873
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PMEPA1 antibody for a 16 amino acid peptide near the center of human PMEPA1. The immunogen is within amino acids 160 - 210 of PMEPA1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718727
靶标信息
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Nedd4 WW binding protein 4; NEDD4 WW domain-binding protein 4; Prostate transmembrane protein androgen induced 1; Protein TMEPAI; Solid tumor-associated 1 protein; Transmembrane prostate androgen-induced protein; transmembrane, prostate androgen induced RNA
基因别名: 2210418I02Rik; AW455466; Erg1.2; N4wbp4; PMEPA1; STAG1; TMEPAI
UniProt ID: (Human) Q969W9
Entrez Gene ID: (Human) 56937, (Rat) 311676, (Mouse) 65112
negative regulation of SMAD protein complex assembly
negative regulation of transforming growth factor beta receptor signaling pathway
androgen receptor signaling pathway
negative regulation of pathway-restricted SMAD protein phosphorylation
biological_process
negative regulation of signal transduction
