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产品信息
PA5-120613
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 300-600 of human PML (NP_1502412)
偶联物
形式
Liquid
浓度
0.88 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914185
产品详细信息
Positive test controls include: Rat spleen, Rat lung, Rat kidney. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Early endosome membrane, Endoplasmic reticulum membrane, Nucleus, PML body, Peripheral membrane protein, nucleolus, nucleoplasm.
Immunogen sequence: AVDARYQRDY EEMASRLGRL DAVLQRIRTG SALVQRMKCY ASDQEVLDMH GFLRQALCRL RQEEPQSLQA AVRTDGFDEF KVRLQDLSSC ITQGKDAAVS KKASPEAAST PRDPIDVDLP EEAERVKAQV QALGLAEAQP MAVVQSVPGA HPVPVYAFSI KGPSYGEDVS NTTTAQKRKC SQTQCPRKVI KMESEEGKEA RLARSSPEQP RPSTSKAVSP PHLDGPPSPR SPVIGSEVFL PNSNHVASGA GEAEERVVVI SSSEDSDAEN SSSRELDDSS SESSDLQLEG PSTLRVLDEN L
靶标信息
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions. [Uniprot]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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