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Invitrogen
PNMT Monoclonal Antibody (OTI1D2)
Product Details
MA5-25530
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Non-human primate,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI1D2
Immunogen
Full length human recombinant protein of PNMT produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723492
Target Information
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Noradrenaline N-methyltransferase; phenylethanolamine N-methylase; Phenylethanolamine N-methyltransferase; PNMTase
Gene Aliases: PENT; PNMT; PNMTase
UniProt ID: (Human) P11086, (Mouse) P40935, (Rat) P10937
Entrez Gene ID: (Human) 5409, (Dog) 491023, (Mouse) 18948, (Rat) 24661
methylation
epinephrine biosynthetic process
catecholamine biosynthetic process
norepinephrine metabolic process
response to hypoxia
response to cold
response to water deprivation
response to activity
adrenal gland development
response to corticosteroid
response to insulin
social behavior
response to isolation stress
response to immobilization stress
response to peptide hormone
response to ethanol
response to ether
S-adenosylhomocysteine metabolic process
S-adenosylmethionine metabolic process
sensory perception of taste
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to dexamethasone stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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