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产品信息
PA5-32006
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 444 and 680 of Human PNPLA8
偶联物
形式
Liquid
浓度
0.84 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2549479
产品详细信息
Recommended positive controls: Jurkat.
Predicted reactivity: Mouse (92%), Rabbit (94%), Chicken (84%), Rhesus Monkey (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calcium-independent phospholipase A2-gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-2; iPLA2-gamma; membrane-associated calcium-independent phospholipase A2 gamma; patatin-like phospholipase domain containing 8; Patatin-like phospholipase domain-containing protein 8; PNPLA-gamma
基因别名: BM-043; IPLA2-2; IPLA22; IPLA2G; iPLA2gamma; MMLA; PNPLA-gamma; PNPLA8
UniProt ID: (Human) Q9NP80
Entrez Gene ID: (Human) 50640
prostaglandin biosynthetic process
fatty acid metabolic process
cell death
arachidonic acid metabolic process
phosphatidylcholine catabolic process
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
linoleic acid metabolic process
phosphatidylethanolamine catabolic process
arachidonic acid secretion
