Invitrogen

POC1B Polyclonal Antibody

POC1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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POC1B Antibody (PA5-24495) in IHC (P)

Immunohistochemistry analysis of POC1B in formalin fixed and paraffin embedded human testis tissue. Samples were incubated with POC1B polyclonal antibody (Product # PA5-24495) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.

POC1B Antibody in Immunocytochemistry (ICC/IF)

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产品信息

PA5-24495

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:100

免疫细胞化学 (ICC/IF)

查看6篇已发表文章 6篇已发表文章

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 321-350 amino acids from the C-terminal region of human WDR51B

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2541995

靶标信息

Required for ciliogenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Tubulin posttranslational modifications modify the atypical spermatozoon centriole.

microPublication biology

Turner KA,Kluczynski DF,Hefner RJ,Moussa RB,Slogar JN,Thekkethottiyil JB,Prine HD,Crossley ER,Flanagan LJ,LaBoy MM,Moran MB,Boyd TG,Kujawski BA,Ruble K,Pap JM,Jaiswal A,Shah TA,Sindhwani P,Avidor-Reiss T

PA5-24495 was used in Immunohistochemistry (Paraffin), Western Blot, Inhibition Assay to examine three post-translational modifications, acetylation, glutamylation, and glycylation of the protein tubulin in human and cattle sperm.

Fri Dec 02 00:00:00 UTC 2022

The human sperm basal body is a complex centrosome important for embryo preimplantation development.

Molecular human reproduction

Amargant F,Pujol A,Ferrer-Vaquer A,Durban M,Martínez M,Vassena R,Vernos I

PA5-24495 was used in Western Blotting and Immunocytochemistry to reveal that the sperm basal body is a complex organelle which converts to a centrosome after fertilization, ensuring the early steps of embryogenesis and successful compaction.

Tue Nov 02 00:00:00 UTC 2021

The human sperm basal body is a complex centrosome important for embryo preimplantation development.

Molecular human reproduction

Amargant F,Pujol A,Ferrer-Vaquer A,Durban M,Martínez M,Vassena R,Vernos I

Tue Nov 02 00:00:00 UTC 2021

WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity.

eLife

Steib E,Laporte MH,Gambarotto D,Olieric N,Zheng C,Borgers S,Olieric V,Le Guennec M,Koll F,Tassin AM,Steinmetz MO,Guichard P,Hamel V

PA5-24495 was used in Immunocytochemistry to reveal that POC16 and its human homolog WDR90 are components of the microtubule wall along the central core region of the centriole.

Fri Sep 18 00:00:00 UTC 2020

WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity.

eLife

Steib E,Laporte MH,Gambarotto D,Olieric N,Zheng C,Borgers S,Olieric V,Le Guennec M,Koll F,Tassin AM,Steinmetz MO,Guichard P,Hamel V

PA5-24495 was used in Immunocytochemistry to reveal that POC16 and its human homolog WDR90 are components of the microtubule wall along the central core region of the centriole.

Fri Sep 18 00:00:00 UTC 2020

PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN.

eLife

Sydor AM,Coyaud E,Rovelli C,Laurent E,Liu H,Raught B,Mennella V

Published figure using POC1B polyclonal antibody (Product # PA5-24495) in Immunofluorescence

Fri Aug 31 00:00:00 UTC 2018

Human microcephaly protein RTTN interacts with STIL and is required to build full-length centrioles.

Nature communications

Chen HY,Wu CT,Tang CC,Lin YN,Wang WJ,Tang TK

PA5-24495 was used in Immunocytochemistry to show that human microcephaly protein RTTN directly interacts with STIL and acts downstream of STIL-mediated centriole assembly, contributing to building full-length centrioles.