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POLE Antibody (PA5-78113) in ICC/IF
POLE Polyclonal Antibody detects POLE protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: POLE protein stained by POLE Polyclonal Antibody (Product # PA5-78113) diluted at 1:2,500. Red: phalloidin, a cytoskeleton marker, diluted at 1:100.
产品信息
PA5-78113
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human POLE. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.34 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736449
产品详细信息
Positive Control: K562
Predicted Reactivity: Mouse (90%), Rat (90%), Bovine (94%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
POLE (Polepsi) is present in proliferating cells and is implicated in repair of UV-damaged DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'-5' exodeoxyribonuclease; DNA polymerase epsilon catalytic subunit A; DNA polymerase epsilon catalytic subunit protein; DNA polymerase II subunit A; polymerase (DNA directed), epsilon, catalytic subunit; polymerase (DNA) epsilon, catalytic subunit
基因别名: CRCS12; FILS; POLE; POLE1
UniProt ID: (Human) Q07864
Entrez Gene ID: (Human) 5426
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
DNA synthesis involved in DNA repair
DNA replication
DNA replication initiation
base-excision repair, gap-filling
nucleotide-excision repair, DNA gap filling
embryonic organ development
nucleic acid phosphodiester bond hydrolysis
