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POLE3 Antibody (PA5-76947) in ICC/IF
Immunofluorescence analysis of POLE3 in U2OS cells. Samples were treated with UV-A laser (cell damage treatment) and incubated with POLE3 polyclonal antibody (Product # PA5-76947), followed by gamma H2AX (green, DNA damage marker) and DAPI (nuclear staining).
产品信息
PA5-76947
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human POLE3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720674
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: arsenic transactivated protein; Arsenic-transactivated protein; AsTP; CHRAC 17; CHRAC-17; Chromatin accessibility complex 17 kDa protein; DNA polymerase epsilon p17 subunit; DNA polymerase epsilon subunit 3; DNA polymerase epsilon subunit p17; DNA polymerase epsilon, subunit 3; DNA polymerase II subunit 3; histone fold protein CHRAC17; huCHRAC17; NF-YB-like protein; polymerase (DNA directed), epsilon 3 (p17 subunit); polymerase (DNA directed), epsilon 3, accessory subunit; polymerase (DNA) epsilon 3, accessory subunit; YB-like protein 1; YBL1
基因别名: 1810034K18Rik; CHARAC17; CHRAC17; p17; POLE3; YBL1
UniProt ID: (Human) Q9NRF9, (Mouse) Q9JKP7
Entrez Gene ID: (Human) 54107, (Mouse) 59001
