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POLR1D Antibody (PA5-103802) in ICC/IF
Immunocytochemistry analysis of POLR1D in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with POLR1D polyclonal antibody (Product # PA5-103802) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-103802
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human POLR1D, corresponding to a region within C-terminal amino acids.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853135
产品详细信息
Antibody detects endogenous levels of total POLR1D.
靶标信息
The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AC19; DNA-directed RNA polymerase I 16 kDa polypeptide; DNA-directed RNA polymerase I subunit D; DNA-directed RNA polymerases I and III subunit RPAC2; hRPA19; polymerase (RNA) I polypeptide D; polymerase (RNA) I polypeptide D, 16kDa; polymerase (RNA) I subunit D; Protein POLR1D, isoform 2; RNA polymerase 1-3; RNA polymerase I 16 kDa subunit; RNA polymerases I and III subunit AC2; RPA16; RPC16
基因别名: 1110003G10Rik; AC19; POLR1C; POLR1D; RPA16; RPA9; RPAC2; RPC16; RPO1-3; TCS2
UniProt ID: (Human) P0DPB5, (Mouse) P97304
Entrez Gene ID: (Human) 51082, (Mouse) 20018, (Rat) 360762
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of gene expression, epigenetic
transcription, DNA-templated
transcription from RNA polymerase I promoter
