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产品信息
PA5-36498
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C-terminual of human POM121
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553555
产品详细信息
This antibody detects endogenous protein at a molecular weight of 121 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM 121A), NUP121 (nucleoporin Nup121) or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spiced isoforms and belongs to the POM121 family. Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to nucleus membrane and endoplasmic reticulum membrane. An essential component of the nuclear pore complex (NPC), POM121 is mandatory for nuclear envelope formation and may play a role in biogenesis of the NPC. POM121 associates with the central spoke ring complex and is involved in anchoring components of the pore complex to the pore membrane by way of its F-X-F-G repeat-containing domain. POM121 overexpression induces the formation of cytoplasmic annulate lamellae (AL).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Nuclear envelope pore membrane protein POM 121; Nuclear envelope pore membrane protein POM 121A; nuclear pore membrane glycoprotein 121 kD; nuclear pore membrane protein 121; nuclear pore membrane protein 121 kDa; nuclear pore membrane protein 121-2; Nucleoporin Nup121; P145; POM121 membrane glycoprotein; POM121 membrane glycoprotein C; POM121B; Pore membrane protein of 121 kDa; pore membrane protein of 121 kDa C
基因别名: 2610027A18Rik; C80273; KIAA0618; mKIAA0618; NUP121; P145; POM121; POM121-2; POM121A
UniProt ID: (Human) Q96HA1, (Rat) P52591, (Mouse) Q8K3Z9
Entrez Gene ID: (Human) 9883, (Human) 100101267, (Rat) 113975, (Mouse) 107939
RNA export from nucleus
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
intracellular transport of virus
regulation of cellular response to heat
nuclear pore organization
protein transport
mRNA transport
transport
