Invitrogen

POMK Polyclonal Antibody

View all (25) POMK antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-90533

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human POMK (NP_1156131)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.83 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806112

Product Specific Information

Immunogen sequence: MEKQPQNSRR GLAPREVPPA VGLLLIMALM NTLLYLCLDH FFIAPRQSTV DPTHCPYGHF RIGQMKNCSP WLSCEELRTE VRQLKRVGEG AVKRVFLSEW KEHKVALSQL TSLEMKDDFL HGLQMLKSLQ GTHVVTLLGY CEDDNTMLTE YHPLGSLSNL EETLNLSKYQ NVNTWQHRLE LAMDYVSIIN YLHHSPVGTR VMCDSNDLPK TLSQYLLTSN FSILANDLDA LPLVNHSSGM LVKCGHRELH GDFVAPEQLW PYGEDVPFHD DLMPSYDEKI DIWKIPDISS FLLGHIEGSD MVRFHLFDIH KACKSQTPSE RPTAQDVLET YQKVLDTLRD AMMSQAREML; Positive Samples: mouse kidney, rat kidney; Cellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein

Target Information

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: POMK; probable inactive protein kinase-like protein SgK196; Protein kinase-like protein SgK196; Protein O-mannose kinase; Sugen kinase 196

View more View less

Gene Aliases: 4930444A02Rik; Pomk; RGD1310810; Sgk196

View more View less

UniProt ID: (Rat) Q4V8A9, (Mouse) Q3TUA9

View more View less

Entrez Gene ID: (Rat) 306549, (Mouse) 74653

View more View less

Function(s)
protein kinase activity ATP binding phosphotransferase activity, alcohol group as acceptor carbohydrate kinase activity nucleotide binding phosphofructokinase activity phosphorylase kinase regulator activity cobinamide kinase activity phytol kinase activity kinase activity phosphatidylinositol phosphate kinase activity cyclin-dependent protein serine/threonine kinase regulator activity transferase activity transferase activity, transferring phosphorus-containing groups phenol kinase activity cyclin-dependent protein kinase activating kinase regulator activity inositol tetrakisphosphate 2-kinase activity heptose 7-phosphate kinase activity aminoglycoside phosphotransferase activity phosphatidylinositol 3-kinase activity eukaryotic elongation factor-2 kinase regulator activity eukaryotic elongation factor-2 kinase activator activity LPPG:FO 2-phospho-L-lactate transferase activity cytidine kinase activity glycerate 2-kinase activity (S)-lactate 2-kinase activity phosphoserine:homoserine phosphotransferase activity L-seryl-tRNA(Sec) kinase activity phosphocholine transferase activity polynucleotide 5'-hydroxyl-kinase activity ATP-dependent polynucleotide kinase activity GTP-dependent polynucleotide kinase activity farnesol kinase activity CTP:2-trans,-6-trans-farnesol kinase activity geraniol kinase activity geranylgeraniol kinase activity CTP:geranylgeraniol kinase activity prenol kinase activity 1-phosphatidylinositol-5-kinase activity 1-phosphatidylinositol-3-phosphate 4-kinase activity phosphatidylinositol-3,4-bisphosphate 5-kinase activity phosphatidylinositol bisphosphate kinase activity inositol-3,4,6-trisphosphate 1-kinase activity inositol 5-diphosphate pentakisphosphate 5-kinase activity inositol diphosphate tetrakisphosphate kinase activity
Process(es)
neuron migration protein phosphorylation protein O-linked glycosylation brain development learning or memory sensory perception of pain carbohydrate phosphorylation neuromuscular process phosphorylation
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support