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POMT1 Antibody (PA5-29032) in WB
Western Blot analysis of POMT1 was performed by separating 30 µg of Whole cell extracts by 7.5% SDS-PAGE. Proteins were transferred to a membrane and probed with a POMT1 Polyclonal Antibody (Product # PA5-29032) at a dilution of 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-29032
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 420 and 697 of Human POMT1
偶联物
形式
Liquid
浓度
0.79 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546508
产品详细信息
Recommended positive controls: NT2D1, IMR32, U87-MG.
Predicted reactivity: Mouse (80%), Chimpanzee (99%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dolichyl-phosphate-mannose--protein mannosyltransferase 1; FLJ37239; Protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1; testis tissue sperm-binding protein Li 57p
基因别名: LGMD2K; MDDGA1; MDDGB1; MDDGC1; POMT1; RT
UniProt ID: (Human) Q9Y6A1
Entrez Gene ID: (Human) 10585
cell wall mannoprotein biosynthetic process
carbohydrate metabolic process
protein O-linked glycosylation
multicellular organism development
extracellular matrix organization
protein O-linked mannosylation
chain elongation of O-linked mannose residue
regulation of endoplasmic reticulum unfolded protein response
