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产品信息
PA5-42684
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human POMT1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2576278
产品详细信息
Peptide sequence: LTFQILLLPV VLQHISDHLC RSQLQRSIFS ALVVAWYSSA CHVSNTLRPL
Sequence homology: Cow: 86%; Dog: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 77%; Rat: 86%
靶标信息
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dolichyl-phosphate-mannose--protein mannosyltransferase 1; FLJ37239; Protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1; testis tissue sperm-binding protein Li 57p
基因别名: LGMD2K; MDDGA1; MDDGB1; MDDGC1; POMT1; RT
UniProt ID: (Human) Q9Y6A1
Entrez Gene ID: (Human) 10585
cell wall mannoprotein biosynthetic process
carbohydrate metabolic process
protein O-linked glycosylation
multicellular organism development
extracellular matrix organization
protein O-linked mannosylation
chain elongation of O-linked mannose residue
regulation of endoplasmic reticulum unfolded protein response
