Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 2
PON2 Antibody (PA5-115781) in IHC (P)
Immunohistochemistry analysis of PON2 in mouse spleen tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115781) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.
产品信息
PA5-115781
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PON2(Accession Q15165), corresponding to amino acid residues K249-P299.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900416
产品详细信息
Antibody detects endogenous levels of total PON2.
靶标信息
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: A esterase 2; A-esterase 2; Aromatic esterase 2; arylesterase 2; paraoxonase nirs; PON 2; Serum aryldialkylphosphatase 2; Serum paraoxonase/arylesterase 2
基因别名: 6330405I24Rik; AI481612; PON2
UniProt ID: (Human) Q15165, (Mouse) Q62086, (Rat) Q6AXM8
Entrez Gene ID: (Human) 5445, (Mouse) 330260, (Rat) 296851
