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POU4F3 Antibody (PA5-78116) in IHC (P)
POU4F3 Polyclonal Antibody detects POU4F3 protein at cytoplasm and nucleus in mouse eye by immunohistochemical analysis. Sample: Paraffin-embedded mouse eye. POU4F3 Polyclonal Antibody (Product # PA5-78116) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-78116
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human POU4F3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.11 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736450
产品详细信息
Positive Control: HeLa nuclear extract
Predicted Reactivity: Rat (98%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
POU4F3 encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in this gene are the cause of non-syndromic sensorineural deafness autosomal dominant type 15.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain-3C; brain-specific homeobox POU domain protein 3C; Brain-specific homeobox/POU domain protein 3C; Brn-3.1; brn-3C; MGC138412; POU domain, class 4, transcription factor 3
基因别名: Brn-3.1; Brn-3c; Brn3.1; BRN3C; ddl; DFNA15; dreidel; POU4F3
UniProt ID: (Human) Q15319, (Mouse) Q63955
Entrez Gene ID: (Human) 5459, (Mouse) 18998
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
DNA binding
sequence-specific DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
sensory perception of sound
vestibulocochlear nerve development
retinal ganglion cell axon guidance
inner ear morphogenesis
auditory receptor cell differentiation
positive regulation of transcription from RNA polymerase II promoter
axon extension
inner ear development
neuromuscular process controlling balance
neuron apoptotic process
inner ear receptor cell differentiation
visual perception
