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产品信息
MA5-21327
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
8F9
抗原
POU6F2 (NP_009183, 2 a.a. ~ 87 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.2-1.0 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2608269
产品详细信息
Peptide Sequence: IAGQVSKPLL SVRSEMNAEL RGEDKAATSD SELNEPLLAP VESNDSEDTP SKLFGARGNP ALSDPGTPDQ HQASQTHPPF PVGPQP
靶标信息
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: POU domain class 6 transcription factor 2; POU domain, class 6, transcription factor 2; Retina-derived POU domain factor 1; retina-derived POU-domain factor-1; RPF-1; Wilms tumor suppressor locus
基因别名: POU6F2; RPF-1; RPF1; WT5; WTSL
UniProt ID: (Human) P78424
Entrez Gene ID: (Human) 11281
