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PP1 alpha Antibody (PA5-119781) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded rat large intestine tissue using PP1 alpha Polyclonal Antibody (Product # PA5-119781). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the PP1 alpha antibody a... View More
产品信息
PA5-119781
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within human PPP1CA aa 291-330
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2913353
产品详细信息
Positive Control: MCF-7 cell lysate, A549 cell lysate, K562 cell lysate, Hela cell lysate, rat brain tissue lysate, mouse brain tissue lysate, rat large intestine tissue, mouse kidney tissue.
Subcellular Location: Nucleus, nucleoplasm, nucleolus, cytoplasm.
靶标信息
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GADD34; MGC15877; MGC1674; PP-1A; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
基因别名: dism2; PP-1A; PP1A; PP1alpha; PPP1A; Ppp1c; PPP1CA
UniProt ID: (Human) P62136, (Mouse) P62137, (Rat) P62138
Entrez Gene ID: (Human) 5499, (Mouse) 19045, (Rat) 24668
glycogen metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
protein dephosphorylation
cell cycle
dephosphorylation
lung development
negative regulation of protein binding
circadian regulation of gene expression
regulation of translational initiation by eIF2 alpha dephosphorylation
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
branching morphogenesis of an epithelial tube
cell division
regulation of canonical Wnt signaling pathway
beta-catenin destruction complex disassembly
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
carbohydrate metabolic process
regulation of translation
female meiotic division
cellular process
rhythmic process
