Invitrogen

PP1 gamma Polyclonal Antibody

PP1 gamma Antibody in Immunocytochemistry (ICC/IF)

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PP1 gamma Antibody (PA5-21671) in ICC/IF

Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PP1 gamma antibody (Product # PA5-21671) at 1:200 dilution.

PP1 gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PP1 gamma Antibody in Western Blot, Immunohistochemistry, Immunoprecipitation (WB, IHC, IP)

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产品信息

PA5-21671

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

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免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

免疫沉淀 (IP)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 2 and 227 of PP1C gamma (Uniprot ID#P36873)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.79 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_11153939

产品详细信息

Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Raji, NIH-3T3.

Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Dog (99%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease.

The EMBO journal

Grochowska KM,Gomes GM,Raman R,Kaushik R,Sosulina L,Kaneko H,Oelschlegel AM,Yuanxiang P,Reyes-Resina I,Bayraktar G,Samer S,Spilker C,Woo MS,Morawski M,Goldschmidt J,Friese MA,Rossner S,Navarro G,Remy S,Reissner C,Karpova A,Kreutz MR

PA5-21671 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate β-amyloid peptide in synapses in Alzheimer's disease.

Wed Feb 15 00:00:00 UTC 2023

Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease.

The EMBO journal

PA5-21671 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate β-amyloid peptide in synapses in Alzheimer's disease.

Wed Feb 15 00:00:00 UTC 2023

Ultrastructural Localization and Molecular Associations of HCV Capsid Protein in Jurkat T Cells.

Frontiers in microbiology

Fernández-Ponce C,Durán-Ruiz MC,Narbona-Sánchez I,Muñoz-Miranda JP,Arbulo-Echevarria MM,Serna-Sanz A,Baumann C,Litrán R,Aguado E,Bloch W,García-Cozar F

Published figure using PP1 gamma polyclonal antibody (Product # PA5-21671) in Western Blot

Wed Sep 30 00:00:00 UTC 2020

Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.

Cell reports

Brieño-Enríquez MA,Moak SL,Toledo M,Filter JJ,Gray S,Barbero JL,Cohen PE,Holloway JK

PA521671 was used in western blot to elucidate how NEK1 regulates cohesin assembly on chromosomes at meiotic prophase I

Tue Oct 18 00:00:00 UTC 2016

Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.

Cell reports

Brieño-Enríquez MA,Moak SL,Toledo M,Filter JJ,Gray S,Barbero JL,Cohen PE,Holloway JK

PA521671 was used in western blot to elucidate how NEK1 regulates cohesin assembly on chromosomes at meiotic prophase I

Tue Oct 18 00:00:00 UTC 2016

Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1γ-WAPL Axis in the Mouse.

Cell reports

Brieño-Enríquez MA,Moak SL,Toledo M,Filter JJ,Gray S,Barbero JL,Cohen PE,Holloway JK

PA521671 was used in western blot to elucidate how NEK1 regulates cohesin assembly on chromosomes at meiotic prophase I

Tue Oct 18 00:00:00 UTC 2016

生物信息学

蛋白别名: MGC1675; MGC2870; PP-1G; PP1C gamma 1; PP1C gamma 2; PP1G; PP1gamma; PP2CG; PP2CGAMMA; PPP2CG; protein phosphatase 1, catalytic subunit, gamma isoform; protein phosphatase 1, catalytic subunit, gamma isozyme; Protein phosphatase 1C catalytic subunit; serine/threonine phosphatase 1 gamma; Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

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基因别名: dis2m1; PP-1G; PP1; PP1C; PPP1CC; PPP1G

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UniProt ID: (Human) P36873, (Mouse) P63087

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Entrez Gene ID: (Human) 5501, (Mouse) 19047

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功能