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PP5 Antibody (PA5-85283) in ICC/IF
PP5 antibody detects PP5 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PP5 protein stained by PP5 antibody (Product # PA5-85283) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-85283
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human PPP5C.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792426
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (85%), Xenopus laevis (85%), Rhesus Monkey (99%), Bovine (97%).
Positive Control: 293T, A431.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; protein phosphatase 5, catalytic subunit; Protein phosphatase T; Serine/threonine-protein phosphatase 5
基因别名: PP5; PPP5; PPP5C; PPT
UniProt ID: (Human) P53041
Entrez Gene ID: (Human) 5536
G-protein alpha-subunit binding
RNA binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
signal transducer activity
protein binding
ATP binding
microtubule binding
lipid binding
heat shock protein binding
identical protein binding
ADP binding
metal ion binding
protein phosphatase
MAPK cascade
negative regulation of protein phosphorylation
DNA repair
transcription, DNA-templated
protein dephosphorylation
mitotic nuclear division
response to lead ion
histone dephosphorylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to morphine
protein heterooligomerization
cellular response to hydrogen peroxide
cellular response to cadmium ion
negative regulation of neuron death
positive regulation of glucocorticoid receptor signaling pathway
