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产品信息
H00008611-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPAP2A (NP_003702.2, 1 a.a. approximately 284 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MFDKTRLPYV ALDVLCVLLA GLPFAILTSR HTPFQRGVFC NDESIKYPYK EDTIPYALLG GIIIPFSIIV IILGETLSVY CNLLHSNSFI RNNYIATIYK AIGTFLFGAA ASQSLTDIAK YSIGRLRPHF LDVCDPDWSK INCSDGYIEY YICRGNAERV KEGRLSFYSG HSSFSMYCML FVALYLQARM KGDWARLLRP TLQFGLVAVS IYVGLSRVSD YKHHWSDVLT GLIQGALVAI LVAVYVSDFF KERTSFKERK EEDSHTTLHE TPTTGNHYPS NHQP
靶标信息
Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.
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生物信息学
蛋白别名: Lipid phosphate phosphohydrolase 1; lipid phosphate phosphohydrolase 1a; PAP-2a; PAP2-alpha; PAP2alpha2; PAPalpha1; Phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a; phosphatidic acid phosphatase type 2A; phosphatidic acid phosphohydrolase type 2a; Phospholipid phosphatase 1; type-2 phosphatidic acid phosphatase alpha
基因别名: LLP1a; LPP1; PAP-2a; PAP2; PLPP1; PPAP2A
UniProt ID: (Human) O14494
Entrez Gene ID: (Human) 8611
protein dephosphorylation
lipid metabolic process
phospholipid metabolic process
protein kinase C-activating G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
germ cell migration
regulation of lipid metabolic process
sphingolipid biosynthetic process
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
phospholipid dephosphorylation
