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PPAT Antibody (MA5-25955) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of human endometrium tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a PPAT monoclonal antibody (Product # MA5-25955).
产品信息
MA5-25955
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1B11
抗原
Human recombinant protein fragment corresponding to amino acids 42-278 of PPAT produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2725081
靶标信息
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amidophosphoribosyltransferase; ATase; EC 2.4.2.14; glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT
基因别名: ATASE; GPAT; PPAT; PRAT
UniProt ID: (Human) Q06203
Entrez Gene ID: (Human) 5471
G1/S transition of mitotic cell cycle
kidney development
purine nucleotide biosynthetic process
'de novo' IMP biosynthetic process
glutamine catabolic process
lactation
purine nucleobase biosynthetic process
nucleoside metabolic process
purine ribonucleoside monophosphate biosynthetic process
organ regeneration
cellular response to insulin stimulus
cellular response to drug
protein homotetramerization
maternal process involved in female pregnancy
