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Product Details
PA5-58584
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PPHLN1. Recombinant protein control fragment (Product #RP-102856).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645819
Product Specific Information
Immunogen sequence: STAPLFTDQP EEPESNTTHG IELFEDSQLT TRSKAIASKT KEIEQVYRQD CETFGMVVKM LIEKDPSLEK SIQFALRQNL HEIESAGQTW QQVPPVRNTE MDHDG
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 70%.
Target Information
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC7 expression repressor; CR; Gastric cancer antigen Ga50; MGC48786; Periphilin-1
Gene Aliases: CR; HSPC206; HSPC232; PPHLN1
UniProt ID: (Human) Q8NEY8
Entrez Gene ID: (Human) 51535
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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