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PPIG Antibody (PA5-87435) in WB
Western blot analysis of PPIG in extracts of various cell lines. Samples were incubated with PPIG Polyclonal antibody (Product # PA5-87435) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-87435
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PPIG (NP_0047832)
偶联物
形式
Liquid
浓度
1.41 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804144
产品详细信息
Immunogen sequence: MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF; Positive Samples: Jurkat, HepG2, HeLa; Cellular Location: Nucleus matrix, Nucleus speckle
靶标信息
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); peptidylprolyl isomerase G (cyclophilin G); PPIase G; Rotamase G; SR-cyclophilin; SR-cyp; SR-related CTD-associated factor 10
基因别名: CARS-Cyp; CYP; PPIG; SCAF10; SRCyp
UniProt ID: (Human) Q13427
Entrez Gene ID: (Human) 9360
