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PPM1E Antibody (PA5-104040) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded PPM1E in mouse spleen tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with PPM1E polyclonal antibody (Product # PA5-104040) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-104040
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PPM1E(Accession Q8WY54), corresponding to amino acid residues A475-C525.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853370
产品详细信息
Antibody detects endogenous levels of total PPM1E.
靶标信息
Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ca(2+)/calmodulin-dependent protein kinase phosphatase N; calmodulin-dependent protein kinase phosphatase N; CaMKN; CaMKP-N; CaMKP-nucleus; nuclear calmodulin-dependent protein kinase phosphatase; Partner of PIX 1; Partner of PIX-alpha; Partner of PIXA; PP2C eta; PP2C-eta; PP2CE; Protein phosphatase 1E; protein phosphatase 1E (PP2C domain containing); Protein phosphatase 1M; protein phosphatase 1M (PP2C domain containing); protein phosphatase 2C eta; protein phosphatase 2C eta-2; Protein phosphatase 2C isoform eta; protein phosphatase, Mg2+/Mn2+ dependent, 1E; protein phosphatase, Mg2+/Mn2+ dependent, 1M
基因别名: 2810423O19Rik; AW049266; AW610647; B930008A12Rik; C77250; CAMKN; CaMKP-N; KIAA1072; mKIAA1072; POPX1; PP2C-eta; PP2CE; PP2Ceta; PP2CH; PPM1E; PPM1M
UniProt ID: (Human) Q8WY54, (Human) Q96MI6, (Mouse) Q5SX30, (Rat) Q80Z30, (Mouse) Q8BU27
Entrez Gene ID: (Human) 22843, (Human) 132160, (Mouse) 320472, (Rat) 360593, (Rat) 686298, (Mouse) 67905
