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PPP1R12B Antibody (PA5-110206) in WB
Western blot analysis of PPP1R12B in extracts of various cell lines. Samples were incubated with PPP1R12B Polyclonal antibody (Product # PA5-110206) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-110206
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2).
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855617
产品详细信息
Immunogen sequence: TFSRSRAERQ AQEQPREKPT DTEGLEGSPE KHEPSAVPAT EAGEGQQPWG RSLDEEPICH RLRCPAQPDK PTTPASPSTS RPSLYTSSHL LWTNRFSVPD SESSETTTNT TTAKEMDKNE NEEADLDEQS SKRLSIRERR RPKERRRGTG INFWTKDEDE TDGSEEVKET WHERLSRLES GGSNPTTSDS YGDRASARAR REAREARLAT LTSRVEEDSN RDYKKLYESA LTENQKLKTK LQEAQLELAD IKSKLEKVAQ QKQEKTSDRS S
靶标信息
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; Myosin phosphatase-targeting subunit 2; Protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12B
基因别名: MYPT2; PP1bp55; PPP1R12B
UniProt ID: (Human) O60237
Entrez Gene ID: (Human) 4660
