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PPP1R15B Antibody (PA5-106285) in IHC (P)
Immunohistochemistry analysis of PPP1R15B in human normal tissues adjacent to liver cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PPP1R15B polyclonal antibody (Product # PA5-106285) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106285
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PPP1R15B(Accession Q5SWA1), corresponding to amino acid residues H633-I683.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853962
产品详细信息
Antibody detects endogenous levels of total PPP1R15B.
靶标信息
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Constitutive repressor of eIF2alpha phosphorylation; CReP; Protein phosphatase 1 regulatory subunit 15B; protein phosphatase 1, regulatory (inhibitor) subunit 15B
基因别名: 1810033K10Rik; AI606441; C530022L24Rik; CREP; MSSGM2; PPP1R15B
UniProt ID: (Human) Q5SWA1, (Mouse) Q8BFW3
Entrez Gene ID: (Human) 84919, (Rat) 304799, (Mouse) 108954
response to oxidative stress
ER overload response
dephosphorylation
response to endoplasmic reticulum stress
response to hydrogen peroxide
regulation of translation
regulation of translational initiation
peptidyl-serine dephosphorylation
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of protein phosphorylation
negative regulation of PERK-mediated unfolded protein response
