Invitrogen

PPP2R2D Polyclonal Antibody

PPP2R2D Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PPP2R2D Antibody (PA5-30763) in IHC (P)

Immunohistochemistry (Paraffin) analysis of PPP2R2D was performed in paraffin-embedded mouse duodenum tissue using PPP2R2D Polyclonal Antibody (Product # PA5-30763) at a dilution of 1:500.

PPP2R2D Antibody in Western Blot, Immunoprecipitation (WB, IP)

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产品信息

PA5-30763

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:10,000

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免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫沉淀 (IP)

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 91 and 380 of Human PPP2R2D

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2548237

产品详细信息

Recommended positive controls: IMR32, mouse brain, rat brain.

Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (95%), Xenopus laevis (95%), Chicken (98%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

PPP2R2D is the B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer.

NAR cancer

Cairns J,Ly RC,Niu N,Kalari KR,Carlson EE,Wang L

PA5-30763 was used in Western Blotting to demonstrate that in addition to its role in cell cycle regulation, CDC25B functions as a regulator of protein phosphatase 2A (PP2A), a major cellular Ser/Thr phosphatase, through its direct interaction with PP2A catalytic subunit.

Tue Dec 01 00:00:00 UTC 2020

CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer.

NAR cancer

Cairns J,Ly RC,Niu N,Kalari KR,Carlson EE,Wang L

Tue Dec 01 00:00:00 UTC 2020

CDC25B partners with PP2A to induce AMPK activation and tumor suppression in triple negative breast cancer.

NAR cancer

Cairns J,Ly RC,Niu N,Kalari KR,Carlson EE,Wang L

Tue Dec 01 00:00:00 UTC 2020

生物信息学

蛋白别名: PP2A subunit B isoform B55-delta; PP2A subunit B isoform delta; PP2A subunit B isoform PR55-delta; PP2A subunit B isoform R2-delta; PP2A, subunit B, B-delta isoform; PP2A, subunit B, B55-delta isoform; PP2A, subunit B, PR55-delta isoform; PP2A, subunit B, R2-delta isoform; protein phosphatase 2 regulatory subunit B, delta; protein phosphatase 2, regulatory subunit B, delta isoform; protein phosphatase 2A B regulatory subunit delta isoform; protein phosphatase 2A, regulatory subunit B, delta isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

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基因别名: 1300017E19Rik; D7Ertd753e; KIAA1541; MDS026; PPP2R2D

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UniProt ID: (Human) Q66LE6, (Rat) P56932, (Mouse) Q925E7

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Entrez Gene ID: (Human) 55844, (Rat) 246255, (Mouse) 52432

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功能

protein phosphatase type 2A regulator activity phosphatidate phosphatase activity protein phosphatase

参与通路

mitotic nuclear division exit from mitosis regulation of protein phosphatase type 2A activity cell division signal transduction dephosphorylation regulation of catalytic activity cell cycle