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PPP2R5A Antibody (PA5-106739) in ICC/IF
Immunocytochemistry analysis of PPP2R5A in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with PPP2R5A polyclonal antibody (Product # PA5-106739) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-106739
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PPP2R5A(Accession Q15172), corresponding to amino acid residues K320-R370.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854407
产品详细信息
Antibody detects endogenous levels of total PPP2R5A.
靶标信息
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC131915; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A, B subunit, B' alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; PP2A, B subunit, R5 alpha isoform; PP2CB; PR61alpha; protein phosphatase 2 regulatory subunit B', alpha; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; protein phosphatase 2, regulatory subunit B', alpha isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
基因别名: B56A; PPP2R5A; PR61A; PR61alpha
UniProt ID: (Human) Q15172, (Mouse) Q6PD03
Entrez Gene ID: (Human) 5525, (Mouse) 226849, (Rat) 312754
