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产品信息
PA5-57740
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2645890
产品详细信息
Immunogen sequence: GKLFDELTAS YKLEKQQEQQ KAQERQELWQ GLEELRLRRL QGTQGAKEAP LQRLTP
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
靶标信息
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
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生物信息学
蛋白别名: FLJ35411; PP2A; PP2A B subunit isoform B'-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; protein phosphatase 2 regulatory subunit B', beta; protein phosphatase 2, regulatory subunit B (B56), beta isoform; protein phosphatase 2, regulatory subunit B', beta isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
基因别名: B'beta; B56B; BC026670; LOC100909468; PPP2R5B; PR61B; rCG_47223
UniProt ID: (Human) Q15173, (Mouse) Q6PD28, (Rat) Q80W83
Entrez Gene ID: (Human) 5526, (Mouse) 225849, (Rat) 309179
regulation of receptor activity
positive regulation of neuron projection development
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of protein complex assembly
regulation of protein autophosphorylation
regulation of protein phosphatase type 2A activity
IRE1-mediated unfolded protein response
positive regulation of transcription from RNA polymerase II promoter
regulation of peptidyl-tyrosine phosphorylation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neurotrophin TRK receptor signaling pathway
negative regulation of G0 to G1 transition
positive regulation of cell cycle arrest
cellular response to growth factor stimulus
regulation of protein phosphorylation
signal transduction
regulation of catalytic activity
