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PPP2R5B Antibody (PA5-89704) in WB
Western blot analysis of PPP2R5B in extracts of U-87MG cells. Samples were incubated with PPP2R5B Polyclonal antibody (Product # PA5-89704) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-89704
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PP2A-B56β/PR61β/PP2A-B56β/PR61β/PPP2R5B (NP_0062351)
偶联物
形式
Liquid
浓度
1.61 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805735
产品详细信息
Immunogen sequence: METKLPPAST PTSPSSPGLS PVPPPDKVDG FSRRSLRRAR PRRSHSSSQF RYQSNQQELT PLPLLKDVPA SELHELLSRK LAQCGVMFDF LDCVADLKGK EVKRAALNEL VECVGSTRGV LIEPVYPDII; Positive Samples: U-87MG; Cellular Location: Cytoplasm
靶标信息
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ35411; PP2A; PP2A B subunit isoform B'-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; protein phosphatase 2 regulatory subunit B', beta; protein phosphatase 2, regulatory subunit B', beta isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
基因别名: B56B; PPP2R5B; PR61B
UniProt ID: (Human) Q15173
Entrez Gene ID: (Human) 5526
regulation of receptor activity
positive regulation of neuron projection development
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of protein complex assembly
regulation of protein autophosphorylation
regulation of protein phosphatase type 2A activity
IRE1-mediated unfolded protein response
positive regulation of transcription from RNA polymerase II promoter
regulation of peptidyl-tyrosine phosphorylation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neurotrophin TRK receptor signaling pathway
negative regulation of G0 to G1 transition
positive regulation of cell cycle arrest
cellular response to growth factor stimulus
