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产品信息
PA5-22148
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 228 of PPP3CB (Uniprot ID#P16298)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11157233
产品详细信息
Recommended positive controls: HeLa, Molt-4, mouse brain.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (83%), Xenopus laevis (83%), Rabbit (99%), Chicken (96%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcineurin A beta; calcineurin A2; Calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic subunit; CNA beta; PP2BA beta; protein phosphatase 2B, catalytic subunit, beta isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase from PCR fragment H32; RP11-345K20.1; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
基因别名: 1110063J16Rik; CALNA2; CALNB; CNA2; Cnab; CnAbeta; PP2Bbeta; PPP3CB
UniProt ID: (Human) P16298, (Mouse) P48453
Entrez Gene ID: (Human) 5532, (Mouse) 19056
protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
drug binding
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
protein dimerization activity
phosphoprotein phosphatase activity
calcium-dependent protein serine/threonine phosphatase activity
hydrolase activity
metal ion binding
protein heterodimerization activity
protein phosphatase
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
signal transduction
Wnt signaling pathway, calcium modulating pathway
heart development
learning
memory
dephosphorylation
calcium ion regulated exocytosis
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
social behavior
cellular response to drug
positive regulation of insulin secretion involved in cellular response to glucose stimulus
Fc-epsilon receptor signaling pathway
T cell proliferation
T cell activation
T cell homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
axon extension
regulation of insulin secretion
positive regulation of NFAT protein import into nucleus
response to stress
regulation of gene expression
