Invitrogen

PPT1 Polyclonal Antibody

查看其他12个PPT1抗体

抗体检测数据 (2)

PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PPT1 Antibody (PA5-86510) in IHC (P)

Immunohistochemical analysis of PPT1 in paraffin-embedded human breast carcinoma tissue. Sample was incubated with polyclonal PPT1 antibody (Product # PA5-86510) using a 1:100 dilution.

PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PPT1 Antibody in Western Blot (WB)

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PPT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of PPT1 in paraffin-embedded human breast carcinoma tissue. Sample was incubated with polyclonal PPT1 antibody (Product # PA5-86510) using a 1:100 dilution.

PPT1 Antibody in Western Blot (WB) — Western blot analysis of PPT1 in Lane 1: A549 whole cell lysate (40 µg), Lane 2: HepG2 whole cell lysate (40 µg), Lane 3: brain tissue lysate of mouse (40 µg), Lane 4: Spleen tissue lysate of rat (40 µg). Sample was incubated with PPT1 polyclonal antibody (Product # PA5-86510) using a 1:1000 dilution.

产品信息

PA5-86510

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide, corresponding to amino acids 50-100 of Human CLN1.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2803285

产品详细信息

Purity is > 95% by SDS-PAGE.

靶标信息

The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 3.1.2.22; ceroid-palmitoyl-palmitoyl-protein thioesterase 1; Palmitoyl-protein hydrolase 1; Palmitoyl-protein thioesterase 1; PPT-1

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基因别名: 9530043G02Rik; AA960502; C77813; CLN1; D4Ertd184e; INCL; PPT; PPT1

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UniProt ID: (Human) P50897, (Rat) P45479, (Mouse) O88531

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Entrez Gene ID: (Human) 5538, (Rat) 29411, (Mouse) 19063

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palmitoyl-(protein) hydrolase activity palmitoyl-CoA hydrolase activity hydrolase activity palmitoyl hydrolase activity protein modifying enzyme

protein depalmitoylation receptor-mediated endocytosis pinocytosis lysosomal lumen acidification chemical synaptic transmission neurotransmitter secretion nervous system development brain development visual perception grooming behavior associative learning adult locomotory behavior protein transport lipid catabolic process sphingolipid catabolic process protein catabolic process negative regulation of cell growth membrane raft organization regulation of phospholipase A2 activity long-chain fatty-acyl-CoA biosynthetic process negative regulation of apoptotic process negative regulation of neuron apoptotic process cellular protein catabolic process positive regulation of receptor-mediated endocytosis positive regulation of pinocytosis neuron development regulation of synapse structure or activity response to stimulus cofactor transport cofactor metabolic process lysosome organization cellular macromolecule catabolic process regulation of synaptic plasticity macromolecule depalmitoylation