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产品信息
H00005547-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PRCP (NP_005031.1, 1 a.a. approximately 496 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGRRALLLLL LSFLAPWATI ALRPALRALG SLHLPTNPTS LPAVAKNYSV LYFQQKVDHF GFNTVKTFNQ RYLVADKYWK KNGGSILFYT GNEGDIIWFC NNTGFMWDVA EELKAMLVFA EHRYYGESLP FGDNSFKDSR HLNFLTSEQA LADFAELIKH LKRTIPGAEN QPVIAIGGSY GGMLAAWFRM KYPHMVVGAL AASAPIWQFE DLVPCGVFMK IVTTDFRKSG PHCSESIHRS WDAINRLSNT GSGLQWLTGA LHLCSPLTSQ DIQHLKDWIS ETWVNLAMVD YPYASNFLQP LPAWPIKVVC QYLKNPNVSD SLLLQNIFQA LNVYYNYSGQ VKCLNISETA TSSLGTLGWS YQACTEVVMP FCTNGVDDMF EPHSWNLKEL SDDCFQQWGV RPRPSWITTM YGGKNISSHT NIVFSNGELD PWSGGGVTKD ITDTLVAVTI SEGAHHLDLR TKNALDPMSV LLARSLEVRH MKNWIRDFYD SAGKQH
靶标信息
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Angiotensinase C; Lysosomal carboxypeptidase C; Lysosomal Pro-X carboxypeptidase; PRCP; Proline carboxypeptidase; Prolylcarboxypeptidase; prolylcarboxypeptidase (angiotensinase C)
基因别名: HUMPCP; PCP; PRCP
UniProt ID: (Human) P42785
Entrez Gene ID: (Human) 5547
regulation of thyroid hormone mediated signaling pathway
plasma kallikrein-kinin cascade
negative regulation of systemic arterial blood pressure
proteolysis
blood coagulation, intrinsic pathway
glucose homeostasis
regulation of blood vessel endothelial cell migration
angiogenesis involved in wound healing
energy homeostasis
regulation of reactive oxygen species metabolic process
