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产品信息
PA5-53543
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2645920
产品详细信息
Immunogen sequence: KHLKRTIPGA ENQPVIAIGG SYGGMLAAWF RMKYPHMVVG ALAASAPIWQ FEDLVPCGVF MKIVTTDFRK SGPHCSESIH RSWDAINRLS NTGSGLQWLT GALHLCSPLT SQDIQHLKDW ISETWVNLAM VDYP
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.
靶标信息
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Angiotensinase C; Lysosomal carboxypeptidase C; Lysosomal Pro-X carboxypeptidase; PRCP; Proline carboxypeptidase; Prolylcarboxypeptidase; prolylcarboxypeptidase (angiotensinase C)
基因别名: HUMPCP; PCP; PRCP
UniProt ID: (Human) P42785
Entrez Gene ID: (Human) 5547
regulation of thyroid hormone mediated signaling pathway
plasma kallikrein-kinin cascade
negative regulation of systemic arterial blood pressure
proteolysis
blood coagulation, intrinsic pathway
glucose homeostasis
regulation of blood vessel endothelial cell migration
angiogenesis involved in wound healing
energy homeostasis
regulation of reactive oxygen species metabolic process
