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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKLPLLLALL FGAVSALHLR SETSTFETPL GAKTQPEDEE TPEQEMEETP CRELEEEEEW GSGSEDASKK DGAVESISVP DMVDKNLTCP EEEDTVKVVG IPGCQTCRYL LVRSLQTFSQ AWFTCRRCYR GNLVSIHNFN INYRIQCSVS ALNQGQVWIG GRITGSGRCR RFQWVDGSRW NFAYWAAHQP WSRGGHCVAL CTRGGYWRRA HCLRRLPFIC SY
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BMPG; Bone marrow proteoglycan; bone-marrow proteoglycan; eosinophil granule major basic protein; eosinophil major basic protein; LPR3; natural killer cell activator; PRG-2; Proteoglycan 2; proteoglycan 2 preproprotein; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
基因别名: BMPG; MBP; MBP1; PRG2; proMBP
UniProt ID: (Human) Q14227
Entrez Gene ID: (Human) 5553