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PRIM1 Antibody (PA5-106653) in IHC (P)
Immunohistochemistry analysis of PRIM1 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PRIM1 polyclonal antibody (Product # PA5-106653) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106653
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human PRIM1(Accession P49642), corresponding to amino acid residues T380-F420.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854321
产品详细信息
Antibody detects endogenous levels of total PRIM1.
靶标信息
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA primase 1; DNA primase 49 kDa subunit; DNA primase small subunit; DNA primase subunit 48; MGC12308; p49; PRI1; primase p49 subunit; primase polypeptide 1, 49kDa; primase, DNA, polypeptide 1 (49kDa)
基因别名: AI324982; p49; PRIM1
UniProt ID: (Human) P49642, (Mouse) P20664
Entrez Gene ID: (Human) 5557, (Mouse) 19075, (Rat) 246327
DNA primase activity
metal ion binding
telomerase activity
RNA helicase activity
DNA-directed RNA polymerase activity
sulfate adenylyltransferase activity
protein binding
RNA guanylyltransferase activity
tRNA guanylyltransferase activity
mannose-phosphate guanylyltransferase activity
transferase activity
nucleotidyltransferase activity
DNA/RNA helicase activity
CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity
phospholactate guanylyltransferase activity
ATP:coenzyme F420 adenylyltransferase activity
UDP-N-acetylgalactosamine diphosphorylase activity
primase
