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PRKAR2A Antibody (PA5-78123) in ICC/IF
PRKAR2A antibody detects PRKAR2A protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 100% MeOH for 5 min. Green: PRKAR2A protein stained by PRKAR2A antibody (Product # PA5-78123) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-78123
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human PKA R2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736438
产品详细信息
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Mouse (95%), Rat (95%), Pig (97%), Chimpanzee (99%), Bovine (96%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cAMP-dependent protein kinase regulatory subunit RII alpha; cAMP-dependent protein kinase type II-alpha regulatory subunit; MGC3606; protein kinase A, RII-alpha subunit; protein kinase, cAMP-dependent, regulatory subunit type II alpha
基因别名: PKR2; PRKAR2; PRKAR2A
UniProt ID: (Human) P13861
Entrez Gene ID: (Human) 5576
