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产品信息
H00025865-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PRKD2 (NP_057541, 1 a.a. approximately 878 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MATAPSYPAG LPGSPGPGSP PPPGGLELQS PPPLLPQIPA PGSGVSFHIQ IGLTREFVLL PAASELAHVK QLACSIVDQK FPECGFYGLY DKILLFKHDP TSANLLQLVR SSGDIQEGDL VEVVLSASAT FEDFQIRPHA LTVHSYRAPA FCDHCGEMLF GLVRQGLKCD GCGLNYHKRC AFSIPNNCSG ARKRRLSSTS LASGHSVRLG TSESLPCTAE ELSRSTTELL PRRPPSSSSS SSASSYTGRP IELDKMLLSK VKVPHTFLIH SYTRPTVCQA CKKLLKGLFR QGLQCKDCKF NCHKRCATRV PNDCLGEALI NGDVPMEEAT DFSEADKSAL MDESEDSGVI PGSHSENALH ASEEEEGEGG KAQSSLGYIP LMRVVQSVRH TTRKSSTTLR EGWVVHYSNK DTLRKRHYWR LDCKCITLFQ NNTTNRYYKE IPLSEILTVE SAQNFSLVPP GTNPHCFEIV TANATYFVGE MPGGTPGGPS GQGAEAARGW ETAIRQALMP VILQDAPSAP GHAPHRQASL SISVSNSQIQ ENVDIATVYQ IFPDEVLGSG QFGVVYGGKH RKTGRDVAVK VIDKLRFPTK QESQLRNEVA ILQSLRHPGI VNLECMFETP EKVFVVMEKL HGDMLEMILS SEKGRLPERL TKFLITQILV ALRHLHFKNI VHCDLKPENV LLASADPFPQ VKLCDFGFAR IIGEKSFRRS VVGTPAYLAP EVLLNQGYNR SLDMWSVGVI MYVSLSGTFP FNEDEDINDQ IQNAAFMYPA SPWSHISAGA IDLINNLLQV KMRKRYSVDK SLSHPWLQEY QTWLDLRELE GKMGERYITH ESDDARWEQF AAEHPLPGSG LPTDRDLGGA CPPQDHDMQG LAERISVL
靶标信息
PRKD2 (PKD2) is a member of the protein kinase D serine/threonine protein kinase family. PRKD2 is a component in the signal transduction pathway induced by phorbol esters and the CCK b gastrin receptor. It exhibits the strongest homology to the serine threonine protein kinases PKD/PKC and PKCnu, particularly in the duplex zinc finger-like cysteine-rich motif, in the pleckstrin homology domain and in the protein kinase domain. In contrast, it shows only a low degree of sequence similarity to other members of the PKC family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: nPKC-D2; Serine/threonine-protein kinase D2
基因别名: HSPC187; nPKC-D2; PKD2; PRKD2
UniProt ID: (Human) Q9BZL6
Entrez Gene ID: (Human) 25865
angiogenesis
positive regulation of endothelial cell proliferation
adaptive immune response
protein phosphorylation
cell adhesion
cell death
positive regulation of endothelial cell migration
peptidyl-serine phosphorylation
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of interleukin-2 production
positive regulation of interleukin-8 production
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
intracellular signal transduction
cellular response to vascular endothelial growth factor stimulus
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
positive regulation of blood vessel endothelial cell migration
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
T cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
endothelial tube morphogenesis
positive regulation of ERK1 and ERK2 cascade
protein kinase D signaling
mitophagy in response to mitochondrial depolarization
positive regulation of histone deacetylase activity
positive regulation of intracellular signal transduction
positive regulation of DNA biosynthetic process
positive regulation of endothelial cell chemotaxis
