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Product Details
PA5-27913
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 44 and 309 of Human PRKX
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545389
Product Specific Information
Recommended positive controls: 293T, A431, mouse brain.
Predicted reactivity: Mouse (88%), Rat (88%), Rhesus Monkey (99%), Chimpanzee (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PRKX is a serine/threonine kinase related to the catalytic subunit of the cAMP-dependent protein kinases. PRKX is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cAMP-dependent protein kinase catalytic subunit PRKX; PKA-related protein kinase; PrKX; Protein kinase PKX1; protein kinase X; protein kinase X-linked; putative serine/threonine kinase; serine/threonine-protein kinase PRKX
Gene Aliases: Pkare; PKX1; PRKX
UniProt ID: (Human) P51817, (Mouse) Q922R0
Entrez Gene ID: (Human) 5613, (Mouse) 19108
angiogenesis
endothelial cell proliferation
cell adhesion
peptidyl-serine phosphorylation
myeloid cell differentiation
regulation of cell adhesion
regulation of cell migration
cell-substrate adhesion
endothelial cell migration
protein autophosphorylation
epithelial tube morphogenesis
kidney morphogenesis
regulation of epithelial cell differentiation involved in kidney development
protein phosphorylation
multicellular organism development
phosphorylation
cell differentiation
Performance Guarantee
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