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PRODH Antibody (PA5-120955) in WB
Western blot analysis of PRODH in extracts of various cell lines. Samples were incubated with PRODH Polyclonal antibody (Product # PA5-120955) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-120955
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human PRODH (NP_057419.4).
偶联物
形式
Liquid
浓度
0.86 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914527
产品详细信息
Positive test controls include: Mouse liver, Mouse kidney, Mouse heart, Rat liver, Rat kidney. The target is usually found in the following locations: Mitochondrion matrix.
Immunogen sequence: IDSRTKLSKH LVVPNAQTGQ LEPLLSRFTE EEELQMTRML QRMDVLAKKA TEMGVRLMVD AEQTYFQPAI SRLTLEMQRK FNVEKPLIFN TYQCYLKDAY DNVTLDVELA RREGWCFGAK LVRGAYLAQE RARAAEIGYE DPINPTYEAT NAMYHRCLDY VLEELKHNAK AKVMVASHNE DTVRFALRRM EELGLHPADH QVYFGQLLGM CDQISFPLGQ AGYPVYKYVP YGPVMEVLPY LSRRALENSS LMKGTHRERQ LLWLELLRRL RTGNLFHRPA
靶标信息
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: p53-induced gene 6 protein; PRODH 1; PRODH 2; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase); Proline dehydrogenase 1, mitochondrial; proline dehydrogenase, mitochondrial; Proline oxidase; Proline oxidase 2; proline oxidase, mitochondrial; SCZD4; tumor protein p53 inducible protein 6
基因别名: HSPOX2; PIG6; POX; POX2; Pro-1; Pro1; PRODH; PRODH1; PRODH2; TP53I6; Ym24d07
UniProt ID: (Human) O43272, (Mouse) Q3UNR4
Entrez Gene ID: (Human) 5625, (Mouse) 19125, (Rat) 680409
