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PRP19 Antibody (PA5-19550) in WB
Western blot analysis of HeLa Whole Cell Lysate using Product # PA5-19550, PRP19 primary antibody at a dilution of 1 µg/mL (lane 1). Staining of Jurkat Whole Cell Lysate at a dilution of 1 µg/mL (lane 2). Blot treated with a secondary HRP-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:3000.
产品信息
PA5-19550
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human PRP19.
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10979215
产品详细信息
Heat mediated antigen retrieval recommended prior to tissue staining.
This antibody is predicted to react with chicken, Xenopus laevis and zebrafish based on sequence homology.
靶标信息
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPso4; Neuronal differentiation-related gene protein; Nuclear matrix protein 200; nuclear matrix protein NMP200 related to splicing factor PRP19; nuclear matrix protein SNEV; Pre-mRNA-processing factor 19; prp19 beta; PRP19/PSO4 homolog; PRP19/PSO4 pre-mRNA processing factor 19 homolog; psoralen 4; RING-type E3 ubiquitin transferase PRP19; Senescence evasion factor
基因别名: AA617263; AL024362; D19Wsu55e; hPSO4; NMP200; PRP19; PRPF19; PSO4; SNEV; UBOX4
UniProt ID: (Human) Q9UMS4, (Mouse) Q99KP6, (Rat) Q9JMJ4
Entrez Gene ID: (Human) 27339, (Mouse) 28000, (Rat) 246216
protein binding
ligase activity
ubiquitin-ubiquitin ligase activity
identical protein binding
ubiquitin protein ligase activity
ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protein polyubiquitination
spliceosomal tri-snRNP complex assembly
spliceosomal complex assembly
generation of catalytic spliceosome for first transesterification step
mRNA splicing, via spliceosome
inner cell mass cell proliferation
DNA repair
double-strand break repair via nonhomologous end joining
mRNA processing
cellular response to DNA damage stimulus
RNA splicing
lipid biosynthetic process
proteasomal protein catabolic process
protein ubiquitination
cellular protein localization
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of mRNA splicing, via spliceosome
positive regulation of astrocyte differentiation
protein K63-linked ubiquitination
signal transduction involved in DNA damage checkpoint
transcription-coupled nucleotide-excision repair
