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产品信息
MA5-38118
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC1038
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 2200-2335 of human PRPF8 (Q6P2Q9)
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2898036
产品详细信息
Positive Samples: HeLa, 293T, Jurkat, Mouse brain, Mouse spleen
Immunogen sequence: MADNPSWDGE KTIIITCSFT PGSCTLTAYK LTPSGYEWGR QNTDKGNNPK GYLPSHYERV QMLLSDRFLG FFMVPAQSSW NYNFMGVRHD PNMKYELQLA NPKEFYHEVH RPSHFLNFAL LQEGEVYSAD REDLYA
靶标信息
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; H PRPC8; p220; Pre-mRNA-processing-splicing factor 8; precursor mRNA processing protein; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; spl; Splicing factor Prp8; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
基因别名: AU019467; D11Bwg0410e; DBF3/PRP8; HPRP8; PRP8; PRPC8; PRPF8; RP13; Sfprp8l; SNRNP220
UniProt ID: (Human) Q6P2Q9, (Mouse) Q99PV0
Entrez Gene ID: (Human) 10594, (Rat) 287530, (Mouse) 192159
