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PRTN3 Antibody (H00005657-D01P) in WB
Western Blot analysis of PRTN3 expression in transfected 293T cell line (H00005657-T01) by PRTN3 MaxPab polyclonal antibody.
Lane 1: PRTN3 transfected lysate(27.80 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PRTN3 transfected lysate(27.80 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00005657-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PRTN3 (AAH96184.1, 1 a.a. approximately 256 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAHRPPSPAL ASVLLALLLS GAARAAEIVG GHEAQPHSRP YMASLQMRGN PGSHFCGGTL IHPSFVLTAA HCLRDIPQRL VNVVLGAHNV RTQEPTQQHF SVAQVFLNNY DAENKLNDIL LIQLSSPANL SASVATVQLP QQDQPVPHGT QCLAMGWGRV GAHDPPAQVL QELNVTVVTF FCRPHNICTF VPRRKAGICF GDSGGPLICD GIIQGIDSFV IWGCATRLFP DFFTRVALYV DWIRSTLRRV EAKGRP
靶标信息
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AGP7; azurophil granule protein 7; C-ANCA antigen; Leukocyte proteinase 3; Myeloblastin; Neutrophil proteinase 4; NP-4; P29; PR-3; Proteinase 3; serine proteinase, neutrophil; Wegener autoantigen; Wegener granulomatosis autoantigen
基因别名: ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; mPR3; NP-4; NP4; P29; PR-3; PR3; PRTN3
UniProt ID: (Human) P24158, (Mouse) Q61096
Entrez Gene ID: (Human) 5657, (Mouse) 19152
