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PSMB1 Antibody (PA5-49648) in ICC/IF
Immunocytochemistry analysis of PSMB1 in HepG2 cells. Samples were incubated in PSMB1 polyclonal antibody (Product # PA5-49648) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
产品信息
PA5-49648
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 214-241 amino acids from the C-terminal region of human PSMB1.
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2635102
靶标信息
PSMB1 is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: beta-6; component C5 of proteasome; Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; proteasome (prosome, macropain) subunit, beta type, 1; proteasome beta 1 subunit; proteasome beta-subunit C5; Proteasome component C5; Proteasome gamma chain; Proteasome subunit beta type-1; Proteasome subunit beta-6; proteasome subunit C5; proteasome subunit HC5; testicular secretory protein Li 45
基因别名: AA409053; C81484; HC5; Lmpc5; PMSB1; PSC5; PSMB1
UniProt ID: (Human) P20618, (Mouse) O09061
Entrez Gene ID: (Human) 5689, (Mouse) 19170
MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
viral process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
proteolysis
proteasomal ubiquitin-independent protein catabolic process
proteolysis involved in cellular protein catabolic process
