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PSMC3 Antibody (PA1-968) in ICC/IF
Immunofluorescence analysis of PSMC3 was performed using 70% confluent log phase Hep G2 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with PSMC3 Rabbit Polyclonal Antibody (Product # PA1-968) at 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Pro... View More
产品信息
PA1-968
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Human recombinant proteasome 19S subunit S6'.
偶联物
形式
Liquid
浓度
Conc. Not Determined
纯化类型
Ammonium sulfate precipitation
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_325951
产品详细信息
PA1-968 detects proteasome 19S subunit S6' from human cells.
PA1-968 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a 48 kDa protein representing proteasome 19S subunit S6' from HeLa cell lysate.
PA1-968 antigen is human recombinant proteasome 19S subunit S6'.
靶标信息
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 26S proteasome AAA-ATPase subunit RPT5; 26S proteasome regulatory subunit 6A; human immunodeficiency virus tat transactivator binding protein-1; MGC8487; proteasome (prosome, macropain) 26S subunit, ATPase, 3; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; rpt5; Tat-binding protein 1; TBP-1; testicular secretory protein Li 42
基因别名: PSMC3; TBP1
UniProt ID: (Human) P17980
Entrez Gene ID: (Human) 5702
MAPK cascade
protein polyubiquitination
blastocyst development
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
viral process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of proteasomal protein catabolic process
negative regulation of nucleic acid-templated transcription
